There are various definitions of alienation that have been used in psychology, sociology, and literature. In psychology, alienation is defined as the feeling of being emotionally separated from others or from one’s own feelings. It is a state of being emotionally distant from others and from one’s own emotions. Sociologically, alienation is often seen as a result of oppressive economic or political systems. This state is typified by feelings of powerlessness, frustration, and despair. Lastly, literary writers often use the term to describe feelings of estrangement, loneliness, and disconnection from the world around them.
When considering the choices listed in your question, the one that is most accurately defined as a feeling of alienation is “the experience of being separated from reality or isolated from one’s thoughts, feelings, or physical being, as in derealization and depersonalization.” This definition comes from the APA Dictionary of Psychology and refers to an individual’s inability to accurately perceive or interact with their environment. This state of alienation can be caused by trauma, substance abuse, or mental health issues.
In conclusion, the definition of alienation that best captures the feeling associated with the term is “the experience of being separated from reality or isolated from one’s thoughts, feelings, or physical being, as in derealization and depersonalization.” This definition is most applicable to the choices listed in the question as it is applicable to both psychological and sociological contexts.